Natural products Synthesis

Many  medicinal drugs come from natural resources such as plants, insects,  corals, etc. One typical example is the synthesis of the commonly known  as Non-steroidal anti-inflammatory, acetylsalicylic acid  (aspirin)  derived from  salicin the natural product isolated from the bark of the  willow tree Salix alba L.

In this post you are required to: 

PART A

Use Google Scholar to search for publications related to the topic. You can use either Plant based synthesis or Natural products Synthesis to start your search.

  • Select a paper that is related to the Synthesis of a Natural product.
  • Take  some time reading the information provided and Indicate the name of the  natural compound the natural resource for and the medicinal uses of the  compound. 
  • Use the name of the compound or the trade name to Search the chemical structure of this drug using MOLVIEW,  
  • take a screenshot of the chemical structure of your molecule and edit the image  identifying and naming all functional groups.
  • Show  the total synthesis scheme (If available) and Circle or highlight the  steps of the synthesis you are familiar with (If any). 
  • If available explain to us how many steps the synthesis involved and how long did it take the research group to make this drug. 

NOTE: Please do not use Aspirin in your search.

PART B

Look at the video: Changing the drug pricing game

Respond to the following questions:

  • What is your stand regarding drug pricing  and the solutions proposed by the author Dr. Peter Bach
  • Do you think the price of drugs should be related with how difficult it is to be prepared?

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